D-Sorbitol-d8
Based on 1 Customer Validation
D-Sorbitol-d8 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.9%
- CAS 番号: 287962-59-8
- 分子式: C6H6D8O6
- 分子量:190.22
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 287962-59-8
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非標識Cas 50-70-4
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性状 Solid
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分子量 190.22
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分子式 C6H6D8O6
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Color White to off-white
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SMILES
OC([2H])([2H])[C@](O)([2H])[C@](O)([2H])[C@@](O)([2H])[C@](O)([2H])C([2H])([2H])O
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別名
Sorbitol-d8; D-Glucitol-d8
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
H2O : 100 mg/mL (525.71 mM; Need ultrasonic)
DMSO : 100 mg/mL (525.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Ranjeet Prasad Dash, et al. Use of sorbitol as pharmaceutical excipient in the present day formulations - issues and challenges for drug absorption and bioavailability. Drug Dev Ind Pharm. 2019 Sep;45(9):1421-1429. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 5.2571 mL | 26.2854 mL | 52.5707 mL | 131.4268 mL |
| 5 mM | 1.0514 mL | 5.2571 mL | 10.5141 mL | 26.2854 mL | |
| 10 mM | 0.5257 mL | 2.6285 mL | 5.2571 mL | 13.1427 mL | |
| 15 mM | 0.3505 mL | 1.7524 mL | 3.5047 mL | 8.7618 mL | |
| 20 mM | 0.2629 mL | 1.3143 mL | 2.6285 mL | 6.5713 mL | |
| 25 mM | 0.2103 mL | 1.0514 mL | 2.1028 mL | 5.2571 mL | |
| 30 mM | 0.1752 mL | 0.8762 mL | 1.7524 mL | 4.3809 mL | |
| 40 mM | 0.1314 mL | 0.6571 mL | 1.3143 mL | 3.2857 mL | |
| 50 mM | 0.1051 mL | 0.5257 mL | 1.0514 mL | 2.6285 mL | |
| 60 mM | 0.0876 mL | 0.4381 mL | 0.8762 mL | 2.1904 mL | |
| 80 mM | 0.0657 mL | 0.3286 mL | 0.6571 mL | 1.6428 mL | |
| 100 mM | 0.0526 mL | 0.2629 mL | 0.5257 mL | 1.3143 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
D-Sorbitol-d8 関連分類
HY-B0400S 関連分類
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