DCBA-d10
DCBA-d10 is the d10-labeled DCBA (HY-136612). DCBA is the major urinary oxidative metabolite of the insect repellent DEET (HY-B0978). DCBA targets EGFR. DCBA exposure is significantly positively correlated with the risk of liver fibrosis. DCBA can be used in liver fibrosis research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C12H5D10NO3
- 分子量:231.31
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
IC50 & Target
Drug Metabolite[1]
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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非標識Cas 72236-23-8
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分子量 231.31
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分子式 C12H5D10NO3
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SMILES
OC(C1=CC(C(N(C([2H])(C([2H])([2H])[2H])[2H])C([2H])(C([2H])([2H])[2H])[2H])=O)=CC=C1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Lewis RC, et al. Urinary biomarkers of exposure to insecticides, herbicides, and one insect repellent among pregnant women in Puerto Rico. Environmental health : a global access science source. 2014 Nov 19;13:97. [Content Brief]
[2]. Kuklenyik P, et al. On-line solid phase extraction-high performance liquid chromatography-isotope dilution-tandem mass spectrometry approach to quantify N,N-diethyl-m-toluamide and oxidative metabolites in urine. Anal Chim Acta. 2013 Jul 17;787:267-73. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DCBA-d10 関連分類
HY-W706930 関連分類
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Keywords
- DCBA-d10
- Isotope-Labeled Compounds
- Drug Metabolite
- EGFR
- MAPK signaling
- PI3K-Akt
- aldehyde intermediate
- benzyl methyl group
- exposure biomarker
- human urine
- inflammatory
- insect repellent
- liver fibrosis
- on-line SPE-HPLC-APCI-MS/MS
- oxidation
- oxidative stress pathways
- pregnant women
- pro-fibrogenic effects
- receptor tyrosine kinase
- ring-carboxylic acid
- urinary oxidative metabolite
- Inhibitor
- inhibitor
- inhibit