Desmethylnortriptyline
Based on 1 Customer Validation
Desmethylnortriptyline is a metabolite of Nortriptyline (HY-118620). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline (HY-B0527) , and is used to relieve the symptoms of depression.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.95%
- CAS 番号: 4444-42-2
- 分子式: C18H19N
- 分子量:249.35
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
化学情報
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CAS 番号 4444-42-2
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性状 Solid
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分子量 249.35
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分子式 C18H19N
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Color White to off-white
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SMILES
NCC/C=C1C2=CC=CC=C2CCC3=CC=CC=C\13
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (401.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Burch JE, et al. Determination of desmethyl nortriptyline in plasma by gas chromatography before and after treatment with salicylaldehyde. J Chromatogr. 1983 May 13;274:350-4. [Content Brief]
[2]. Shimoda K, et al. The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients. J Clin Psychopharmacol. 2002 Aug;22(4):371-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.0104 mL | 20.0521 mL | 40.1043 mL | 100.2607 mL |
| 5 mM | 0.8021 mL | 4.0104 mL | 8.0209 mL | 20.0521 mL | |
| 10 mM | 0.4010 mL | 2.0052 mL | 4.0104 mL | 10.0261 mL | |
| 15 mM | 0.2674 mL | 1.3368 mL | 2.6736 mL | 6.6840 mL | |
| 20 mM | 0.2005 mL | 1.0026 mL | 2.0052 mL | 5.0130 mL | |
| 25 mM | 0.1604 mL | 0.8021 mL | 1.6042 mL | 4.0104 mL | |
| 30 mM | 0.1337 mL | 0.6684 mL | 1.3368 mL | 3.3420 mL | |
| 40 mM | 0.1003 mL | 0.5013 mL | 1.0026 mL | 2.5065 mL | |
| 50 mM | 0.0802 mL | 0.4010 mL | 0.8021 mL | 2.0052 mL | |
| 60 mM | 0.0668 mL | 0.3342 mL | 0.6684 mL | 1.6710 mL | |
| 80 mM | 0.0501 mL | 0.2507 mL | 0.5013 mL | 1.2533 mL | |
| 100 mM | 0.0401 mL | 0.2005 mL | 0.4010 mL | 1.0026 mL |
Desmethylnortriptyline 関連分類
HY-100651 関連分類
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