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製品番号: HY-Y0284

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Diethyl phthalate

2 Cited Publications

カスタマーレビュー

Based on 2 publication(s) in Google Scholar

Diethyl phthalate is an orally active plasticizer and detergent base. Diethyl phthalate increases the activities of ACP, ALP, SDH, and ALT in liver, muscle, or both tissues. Diethyl phthalate induces dose-dependent mortality and sluggish behavior in freshwater fish. Diethyl phthalate may induce male reproductive toxicity. Diethyl phthalate is added to plastic polymers to help maintain their flexibility.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度: 99.87%
CAS 番号: 84-66-2
分子式: C₁₂H₁₄O₄
分子量:222.24

保管条件:

Store at room temperature 3 years.

In solvent -80°C, 2 years , -20°C, 1 year

Diethyl phthalate 構造式

CAS 番号: 84-66-2

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Aminotransferases (Transaminases) アイソフォーム固有の製品をすべて表示 :

体内実験

Diethyl phthalate (25-100 ppm; continuous/daily single aquatic exposure; 3 days-72 h) causes dose-dependent mortality in the fish species *Cirrhina mrigala*, with 100% mortality observed within 24 h at concentrations of 75 ppm and 100 ppm; exposure at 25 ppm also alters the activities of key metabolic and neurological enzymes^[1].
Diethyl phthalate (p.o.) mainly distributes in the kidneys and liver of rats, and subsequently accumulates in adipose tissue^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Cirrhina mrigala (65 mm length, 4 g weight, 6 fish per group)^[1]
Dosage:

25 ppm, 50 ppm, 75 ppm, 100 ppm (mortality assessment); 25 ppm (enzyme activity assays)
Administration:

aquatic exposure; continuous (mortality assessment); once daily; 3 days (enzyme activity assays)
Result:

Caused 100% mortality within 24 hours in fish exposed to 75 ppm and 100 ppm DEP.
Caused 50% mortality within 72 hours in fish exposed to 50 ppm DEP.
Caused 10% mortality within 72 hours in fish exposed to 25 ppm DEP, with remaining fish surviving the extended 3-day treatment.
Significantly increased liver and muscle acid phosphatase (ACP) and alkaline phosphatase (ALP) activity compared to controls in fish treated with 25 ppm DEP for 3 days.
Significantly increased muscle succinate dehydrogenase (SDH) activity compared to controls in fish treated with 25 ppm DEP for 3 days.
Significantly increased liver alanine aminotransferase (ALT) activity (nearly double) compared to controls in fish treated with 25 ppm DEP for 3 days.
Significantly decreased brain acetylcholinesterase (AchE) activity compared to controls in fish treated with 25 ppm DEP for 3 days.
Significantly increased liver aspartate aminotransferase (AST) activity compared to negative controls (though lower than positive controls) in fish treated with 25 ppm DEP for 3 days.
Showed no significant change in liver SDH activity compared to controls in fish treated with 25 ppm DEP for 3 days.
Showed no significant change in muscle AchE activity compared to controls in fish treated with 25 ppm DEP for 3 days.

化学情報

CAS 番号 84-66-2
性状 Liquid (Density: 1.12 g/cm³)
分子量 222.24
分子式 C₁₂H₁₄O₄
Color Colorless to light yellow
SMILES

O=C(C1=CC=CC=C1C(OCC)=O)OCC
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Publications (2)

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Sci Rep

Integrative network toxicology and experimental evidence reveal mechanisms underlying diethyl phthalate-induced initiation and progression of endometrial cancer. [Abstract]

2026 Feb 10;16(1):8066. PMID: 41667778
Food Chem Toxicol

Integrated network toxicology, molecular docking and transcriptomics reveal the mechanistic role of phthalate esters in metabolic disease pathogenesis. [Abstract]

2026 Jan:207:115855. PMID: 41275904

溶剤 & 溶解度

体外:

DMSO : 200 mg/mL (899.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

4.4996 mL

22.4982 mL

44.9964 mL

5 mM

0.8999 mL

4.4996 mL

8.9993 mL

10 mM

0.4500 mL

2.2498 mL

4.4996 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (278 KB)
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COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Ghorpade N, et al. Toxicity study of diethyl phthalate on freshwater fish Cirrhina mrigala. Ecotoxicol Environ Saf. 2002;53(2):255-258. [Content Brief]

[2]. Weaver JA, et al. Hazards of diethyl phthalate (DEP) exposure: A systematic review of animal toxicology studies. Environ Int. 2020;145:105848. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	4.4996 mL	22.4982 mL	44.9964 mL	112.4910 mL
	5 mM	0.8999 mL	4.4996 mL	8.9993 mL	22.4982 mL
	10 mM	0.4500 mL	2.2498 mL	4.4996 mL	11.2491 mL
	15 mM	0.3000 mL	1.4999 mL	2.9998 mL	7.4994 mL
	20 mM	0.2250 mL	1.1249 mL	2.2498 mL	5.6245 mL
	25 mM	0.1800 mL	0.8999 mL	1.7999 mL	4.4996 mL
	30 mM	0.1500 mL	0.7499 mL	1.4999 mL	3.7497 mL
	40 mM	0.1125 mL	0.5625 mL	1.1249 mL	2.8123 mL
	50 mM	0.0900 mL	0.4500 mL	0.8999 mL	2.2498 mL
	60 mM	0.0750 mL	0.3750 mL	0.7499 mL	1.8748 mL
	80 mM	0.0562 mL	0.2812 mL	0.5625 mL	1.4061 mL
	100 mM	0.0450 mL	0.2250 mL	0.4500 mL	1.1249 mL

Diethyl phthalate

2 Cited Publications

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Diethyl phthalate

MedChemExpress（MCE）の使用を引用している文献 Diethyl phthalate

Aminotransferases (Transaminases) アイソフォーム固有の製品をすべて表示

生物活性

化学情報

Publications (2)

溶剤 & 溶解度

純度とドキュメンテーション

参考文献

Help & FAQs

Complete Stock Solution Preparation Table

Diethyl phthalate 関連分類

HY-Y0284 関連分類