Dopal (purity>80%)
Dopal (purity>80%) is a metabolite and aldehyde neurotoxin of Dopamine (HY-B0451). Dopal (purity>80%) exhibits cytotoxicity, induces α-synuclein oligomerization and aggregation, and is closely associated with the pathogenesis of Parkinson's disease. Dopal (purity>80%) can be used in research related to Parkinson's disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 5707-55-1
- 分子式: C8H8O3
- 分子量:152.15
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
α-synuclein アイソフォーム固有の製品をすべて表示
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生物活性
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α-synuclein Aggregation |
化学情報
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CAS 番号 5707-55-1
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分子量 152.15
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分子式 C8H8O3
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SMILES
O=CCC1=CC=C(O)C(O)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Masato A, et al. DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson's disease. NPJ Parkinsons Dis. 2023 Mar 25;9(1):42. [Content Brief]
[2]. Bloch DN, et al. Scavenging neurotoxic aldehydes using lysine carbon dots. Nanoscale Adv. 2023 Jan 19;5(5):1356-1367. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)