DOTA-NOC
Based on 1 Customer Validation
DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5. DOTA-NOC can be used for labeling with various radiometals, and development of radiopeptide imaging. DOTA-NOC can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.22%
- CAS 番号: 619300-53-7
- 分子式: C69H94N14O17S2
- 分子量:1455.70
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Radionuclide-Drug Conjugates (RDCs) アイソフォーム固有の製品をすべて表示
More
生物活性
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RDC Peptide |
Affinity profiles (IC50(μM)) for human somatostatin receptor (SST) 1-5[1].
| Compound | hsst1 | hsst2 | hsst3 | hsst4 | hsst5 |
| InIII-DOTA-NOC | >10000 | 2.9 | 8 | 227 | 11.2 |
| YIII-DOTA-NOC | >10000 | 3.3 | 26 | >10000 | 10.4 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 619300-53-7
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性状 Solid
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分子量 1455.70
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分子式 C69H94N14O17S2
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Color White to off-white
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別名
DOTA-Nal3-octreotide
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配列
DOTA-{d-Phe}-Cys-{Nal}-{d-Trp}-Lys-Thr-Cys-{Threoninol} (Disulfide bridge: Cys2-Cys7)
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シーケンスの短縮
DOTA-{d-Phe}-C-{Nal}-{d-Trp}-KTC-{Threoninol} (Disulfide bridge: Cys2-Cys7)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 50 mg/mL (34.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6870 mL | 3.4348 mL | 6.8695 mL | 17.1739 mL |
| 5 mM | 0.1374 mL | 0.6870 mL | 1.3739 mL | 3.4348 mL | |
| 10 mM | 0.0687 mL | 0.3435 mL | 0.6870 mL | 1.7174 mL | |
| 15 mM | 0.0458 mL | 0.2290 mL | 0.4580 mL | 1.1449 mL | |
| 20 mM | 0.0343 mL | 0.1717 mL | 0.3435 mL | 0.8587 mL | |
| 25 mM | 0.0275 mL | 0.1374 mL | 0.2748 mL | 0.6870 mL | |
| 30 mM | 0.0229 mL | 0.1145 mL | 0.2290 mL | 0.5725 mL |
DOTA-NOC 関連分類
HY-P2112 関連分類
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