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Emactuzumab

(別名: RG 7155; RO 5509554)
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Based on 1 Customer Validation

Emactuzumab(RG 7155) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor (CSF1R) activation. Emactuzumab has high affinity for CSF-1R with Ki value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT) .

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 97.60%
  • CAS 番号: 1448221-67-7
  • 分子量:144.41 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Emactuzumab
  • Experimental Validation Results for Emactuzumab
  • Experimental Validation Results for Emactuzumab
  • Emactuzumab Chemical Structure
    Emactuzumab 構造式
CAS 番号: 1448221-67-7
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CSF1R Protein, Human (HEK293, HY-P72948) can bind Emactuzumab. The EC50 for this effect is 8.427 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 THP-1 cells with Emactuzumab (HY-P99245, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Emactuzumab Chemical Structure
    1/16
  • Emactuzumab
  • Immobilized CSF1R Protein, Human (HEK293, HY-P72948) can bind Emactuzumab. The EC50 for this effect is 8.427 ng/mL.
  • Flow cytometric analysis of 1.5X106 THP-1 cells with Emactuzumab (HY-P99245, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).