Glutaurine
Based on 1 Customer Validation
Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.15%
- CAS 番号: 56488-60-9
- 分子式: C7H14N2O6S
- 分子量:254.26
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
Glutaurine (100~3000 ug/kg; i.p.) significantly reduces T3 blood levels in a dose-dependent manner, but does not significantly raise T4 blood levels[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:CFY male rats (170~250g)[2]
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Dosage:1, 10, 20 or 50 μg/rat
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Administration:P.o.
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Result:Significantly restored the latency of entry in both the 24 and 48 h tests at the dose of 50 μg/rat.
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Animal Model:Fischer 344 rats[3]
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Dosage:100~3000 ug/kg
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Administration:I.p.
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Result:Significantly reduced T3 blood levels in a dose-dependent manner, but did not significantly raise T4 blood levels.
化学情報
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CAS 番号 56488-60-9
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性状 Solid
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分子量 254.26
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分子式 C7H14N2O6S
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Color White to off-white
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SMILES
OC([C@@H](N)CCC(NCCS(=O)(O)=O)=O)=O
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別名
Litoralon
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
H2O : 125 mg/mL (491.62 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Balázs M, et al. Effects of glutaurine treatment on electroshock-induced amnesia. Antiamnesic action of glutaurine. Neuropeptides. 1988;12(2):55-58. [Content Brief]
[2]. Feuer L, et al. Effect of glutaurine, a newly discovered parathyroid hormone on rat thymus cultures. Acta Morphol Acad Sci Hung. 1978;26(2):87-94. [Content Brief]
[3]. Baskin S, et al. The effect of glutaurine on thyroid hormones in the rat. Neuropeptides. 1987;9(1):45-50. [Content Brief]
[4]. Uemura S, et al. Gamma-glutamyltaurine has potent and long-lasting antiepileptic action as demonstrated by intra-amygdaloid injection in amygdala-kindled rats. Brain Res. 1992;594(2):347-350. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.9330 mL | 19.6649 mL | 39.3298 mL | 98.3246 mL |
| 5 mM | 0.7866 mL | 3.9330 mL | 7.8660 mL | 19.6649 mL | |
| 10 mM | 0.3933 mL | 1.9665 mL | 3.9330 mL | 9.8325 mL | |
| 15 mM | 0.2622 mL | 1.3110 mL | 2.6220 mL | 6.5550 mL | |
| 20 mM | 0.1966 mL | 0.9832 mL | 1.9665 mL | 4.9162 mL | |
| 25 mM | 0.1573 mL | 0.7866 mL | 1.5732 mL | 3.9330 mL | |
| 30 mM | 0.1311 mL | 0.6555 mL | 1.3110 mL | 3.2775 mL | |
| 40 mM | 0.0983 mL | 0.4916 mL | 0.9832 mL | 2.4581 mL | |
| 50 mM | 0.0787 mL | 0.3933 mL | 0.7866 mL | 1.9665 mL | |
| 60 mM | 0.0655 mL | 0.3277 mL | 0.6555 mL | 1.6387 mL | |
| 80 mM | 0.0492 mL | 0.2458 mL | 0.4916 mL | 1.2291 mL | |
| 100 mM | 0.0393 mL | 0.1966 mL | 0.3933 mL | 0.9832 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Glutaurine 関連分類
HY-106608 関連分類
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