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製品番号: HY-N21952

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Heliotridine

Name: Heliotridine
Brand: MedChemExpress
SKU: HY-N21952
Availability: PreOrder

(別名: (+)-Heliotridine)

Heliotridine ((+)-Heliotridine) is a monoesters-type necine base of pyrrolizidine alkaloid with genotoxic and antibacterial properties. Heliotridine can be isolated from the aerial parts of Heliotropium ellipticum, Heliotropium circinatum and other Heliotropium species (Boraginaceae). Heliotridine shows high tolerance in normal human hepatocytes (EC₅₀> 400 μM). Mediated by the organic cation transporter OCT1, Heliotridine exhibits in vitro growth inhibition and weak antibacterial activity against Drechslera tetramera. Heliotridine can be used in infection-related studies of specific pathogenic bacteria.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 520-63-8
分子式: C₈H₁₃NO₂
分子量:155.19

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Heliotridine 構造式

CAS 番号: 520-63-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Heliotridine (2 mg; 0.1 g/mL) exhibits in vitro antimicrobial activity against Drechslera tetramera with a 7 mm zone of inhibition, and shows no measurable activity against all other tested bacteria and fungi^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 520-63-8
分子量 155.19
分子式 C₈H₁₃NO₂
SMILES

OCC1=CCN2[C@@]1([H])[C@@H](O)CC2
別名

(+)-Heliotridine
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. JAIN S C, et al. Antimicrobial activity of pyrrolizidine alkaloids from Heliotropium ellipticum[J]. Chemical and pharmaceutical bulletin, 1987, 35(8): 3487-3489.

[2]. Al-Suhail N, et al. Isolation of Pyrrolizidine Alkaloids from a Newly Recorded Heliotropium Species in Southern Basrah and Evaluation of its Anticancer Potential[J]. Eurasian Journal of Oncology, 2025, 13(3).

[3]. Haas M. Investigation of the hepatotoxic potency of selected genotoxic pyrrolizidine alkaloids and the significance of the DNA damage response[D]. Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau, 2025.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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