HM12
HM12 is a covalent inhibitor of L-/T-type calcium channels. HM12 can strongly inhibit the Cav1.2 (L-type) and Cav3.2 (T-type) calcium channels, and has selectivity for the N-type channels. HM12 produces an irreversible inhibition that persisted after washout. HM12 can be used to study diseases such as hypertension, pain, epilepsy, etc.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2376051-91-9
- 分子式: C25H27Br2NO6
- 分子量:597.29
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Calcium Channel アイソフォーム固有の製品をすべて表示
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生物活性
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Cav1.2 |
Cav3.2 |
HM12 (10 μM) exhibits > 90% inhibitory activity against the Cav3.2 calcium channel and > 60% inhibitory activity against the Cav1.2 calcium channel[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2376051-91-9
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分子量 597.29
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分子式 C25H27Br2NO6
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SMILES
O=C(C1=C(C)NC2=C(C(C(C)(C)CC2)=O)C1C3=CC(Br)=CC(Br)=C3O)OCCOC(C(C)=C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
HM12 関連分類
HY-126336 関連分類
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