Human UGT1A6
Human UGT1A6 is a UDP-glucuronosyltransferase. UGT1A6 catalyzes the glucuronidation of 5-hydroxytryptamine (HY-B1473A), 1-Naphthol (HY-Y1309), and Acetaminophen (HY-66005). Human UGT1A6 can be used in studies related to the pathogenesis of bladder cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
UGT1A6 |
体外実験
UGT1A6 efficiently catalyzes the glucuronidation of 5-hydroxytryptamine (HY-B1473A) (Km = 165 µM) and 1-Naphthol (HY-Y1309) (Km = 43 µM), with no detectable activity toward morphine[1].
Human UGT1A6 is expressed in cells and mediates the glucuronidation of Acetaminophen (HY-66005), with a Km value of 2 mM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
SMILES
[Human UGT1A6]
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. King CD, et al. Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate. Arch Biochem Biophys. 1999 May 1;365(1):156-62. [Content Brief]
[2]. Bock KW, et al. UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects. Methods Enzymol. 2005;400:57-75. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Human UGT1A6 関連分類
HY-E72108 関連分類
Powered by Bioz