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Jasplakinolide

9 Cited Publications
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Based on 9 publication(s) in Google Scholar

Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity.

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  • 純度: 99.56%
  • CAS 番号: 102396-24-7
  • 分子式: C36H45BrN4O6
  • 分子量:709.67
  • 保管条件:

    Sealed storage, away from moisture.

    Powder   -80°C, 2 years , -20°C, 1 year

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Jasplakinolide Chemical Structure
    Jasplakinolide 構造式
  • Experimental Validation Results for Jasplakinolide
  • Experimental Validation Results for Jasplakinolide
  • Experimental Validation Results for Jasplakinolide
  • Experimental Validation Results for Jasplakinolide
  • Experimental Validation Results for Jasplakinolide
CAS 番号: 102396-24-7
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  • Jasplakinolide Chemical Structure
    Jasplakinolide Chemical Structure
    1/16
  • 1/16

    Jasplakinolide purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Sep 17:e00358. [Abstract]

    Customer Validation
     E16.5 fetal mouse ovaries were treated with or without 5 µM Jasplakinolide for 4 days. Jasplakinolide treatment altered the size of the ovaries and the morphology of oocytes.

  • 1/16

    Jasplakinolide purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Sep 17:e00358. [Abstract]

    Customer Validation
     E16.5 fetal mouse ovaries were treated with or without 5 µM Jasplakinolide for 4 days. F-actin showed abnormal aggregation in both multinucleated cysts and oocytes.

  • 1/16

    Jasplakinolide purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Sep 17:e00358. [Abstract]

    Customer Validation
     E16.5 fetal mouse ovaries were treated with or without 5 µM Jasplakinolide for 4 days. The proportion of double-nucleated oocytes increased significantly.

  • 1/16

    Jasplakinolide purchased from MedChemExpress. Usage Cited in: Chin Med J (Engl). 2024 Jan 20;137(2):209-221. [Abstract]

    Customer Validation
     Immunofluorescent staining of F-actin and TRIM59 in T24 cells cultured in flask, 3D matrix gels or 3D matrix gels containing Jas (20 mmol/L).

  • 1/16

    Jasplakinolide purchased from MedChemExpress. Usage Cited in: Cell Mol Gastroenterol Hepatol. 2021;11(3):683-696. [Abstract]

    Customer Validation
     Low doses of Jasplakinolide (actin polymerization inducer) attenuated Fg-induced VP, while both high doses of Jasplakinolide and Cytochalasin D (an inhibitor of actin polymerization) dramatically increased Fg-induced VP.

  • Jasplakinolide