Kievitone
Based on 1 Customer Validation
Kievitone, an isoflavanone, could be isolated from hypocotyls of Phaseolus vulgaris L. infected with Rhizoctonia solani Kühn. Kievitone has antifungal activity and antitumor activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.67%
- CAS 番号: 40105-60-0
- 分子式: C20H20O6
- 分子量:356.37
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Kievitone (0-40 μM; 4 days) inhibits the proliferation of the oestrogen receptor (ER)-positive breast cancer cell lines MCF-7 and T47D and the ER-negative breast cancer cell line SKBR3 (IC50 values 5-18 μM)[2].
Kievitone (0-40 μM; 48 h) inhibits DNA synthesis of MCF-7 cells stimicrolated by insulin-like growth factor 1, insulin-like growth factor 2, basic fibroblast growth factor or transforming growth factor α[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MCF-7, T47D and SKBR3 cells
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Concentration:0-40 μM
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Incubation Time:4 days
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Result:Inhibited breast cancer cell proliferation in a dose-dependent manner.
化学情報
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CAS 番号 40105-60-0
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性状 Solid
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分子量 356.37
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分子式 C20H20O6
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Color White to off-white
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SMILES
O=C1C(COC2=C(C(O)=CC(O)=C12)C/C=C(C)\C)C3=CC=C(C=C3O)O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (280.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8061 mL | 14.0304 mL | 28.0607 mL | 70.1518 mL |
| 5 mM | 0.5612 mL | 2.8061 mL | 5.6121 mL | 14.0304 mL | |
| 10 mM | 0.2806 mL | 1.4030 mL | 2.8061 mL | 7.0152 mL | |
| 15 mM | 0.1871 mL | 0.9354 mL | 1.8707 mL | 4.6768 mL | |
| 20 mM | 0.1403 mL | 0.7015 mL | 1.4030 mL | 3.5076 mL | |
| 25 mM | 0.1122 mL | 0.5612 mL | 1.1224 mL | 2.8061 mL | |
| 30 mM | 0.0935 mL | 0.4677 mL | 0.9354 mL | 2.3384 mL | |
| 40 mM | 0.0702 mL | 0.3508 mL | 0.7015 mL | 1.7538 mL | |
| 50 mM | 0.0561 mL | 0.2806 mL | 0.5612 mL | 1.4030 mL | |
| 60 mM | 0.0468 mL | 0.2338 mL | 0.4677 mL | 1.1692 mL | |
| 80 mM | 0.0351 mL | 0.1754 mL | 0.3508 mL | 0.8769 mL | |
| 100 mM | 0.0281 mL | 0.1403 mL | 0.2806 mL | 0.7015 mL |
Kievitone 関連分類
HY-123351 関連分類
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