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製品番号: HY-W727999

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Koenimbine

Koenimbine is an anticancer agent that can be obtained from the leaves and fruits of Murraya koenigii. Koenimbine can induce apoptosis and necrosis in HT-29 and SW48 cells. Koenimbine can be used in the research of cancer.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 21087-98-9
分子式: C₁₉H₁₉NO₂
分子量:293.36

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Koenimbine 構造式

CAS 番号: 21087-98-9

容量

価格（税別）

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数量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
B16-4A5	IC₅₀	1.2 μM Compound: 13	Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control Inhibition of theophylline-induced melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometric analysis relative to control	[PMID: 23376010]
DU-145	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]
HCT-116	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]
HeLa	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]
HepG2	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]
OVCAR-3	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human OVCAR-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human OVCAR-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]
PA-1	IC₅₀	0.2 μM Compound: 35	Antiproliferative activity against human PA-1 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human PA-1 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34838335]

化学情報

CAS 番号 21087-98-9
分子量 293.36
分子式 C₁₉H₁₉NO₂
SMILES

CC1=CC2=C(NC3=C2C=C(C=C3)OC)C4=C1OC(C)(C=C4)C
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (267 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Astaneh M, et al. Assessment of anti-cancer effects of koenimbine on colon cancer cells. Hum Antibodies. 2020;28(3):185-190. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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