LE 28
Based on 1 publication(s) in Google Scholar
LE 28 is a selective and activity-dependent legumain probe. LE 28 becomes fluorescent only upon binding active legumain. LE 28 can be used for research of cancers and inflammatory diseases.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1416080-97-1
- 分子式: C102H111N10O21S3+
- 分子量:1909.22
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
MedChemExpress(MCE)の使用を引用している文献 LE 28
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生物活性
LE 28 (2 mg/kg, i.v.) signal is detected around the periphery of the tumors at 30 min, with maximal contrast between tumor and normal tissue achieved after 7 hours in HCT-116 xenograft tumor model[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:HCT-116 xenograft tumor model[1]
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Dosage:2 mg/kg
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Administration:i.v.
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Result:Detected the signal around the periphery of the tumors in as early as 30 min, with maximal contrast between tumor and normal tissue achieved after seven hours, and the signal remained constant up to 28 h.
化学情報
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CAS 番号 1416080-97-1
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分子量 1909.22
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分子式 C102H111N10O21S3+
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SMILES
O=S(C1=C(C=CC=C1)C2=C(C=CC(N3C4=CC=CC=C4CC3)=C5)C5=[O+]C6=C2C=CC(N7C8=CC=CC=C8CC7)=C6)(N9CCC(CC9)C(NCCCNC(C%10=CC(C)=C(C(C)=C%10)C(OCC([C@H](CC(O)=O)NC([C@H]%11N(CCC%11)C([C@H](CCC(O)=O)NC(CCCCC[N+]%12=C(/C=C/C=C/C=C%13N(C%14=CC=C(S(=O)(O)=O)C=C%14C\%13(C)C)CC)C(C)(C)C%15=CC(S(=O)([O-])=O)=CC=C%12%15)=O)=O)=O)=O)=O)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)