LPLRF-NH2
LPLRF-NH2 is a member of RFamide peptide with anorexigenic effect. LPLRF-NH2 increases arterial blood pressure and modulates the electrical activity of brainstem neurons.
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- CAS 番号: 88280-21-1
- 分子式: C32H53N9O5
- 分子量:643.82
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
YMRF-NH2 (0.1 nM-1 μM) inhibits Forskolin-induced production of cAMP in CHO cells[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
LPLRF-NH2 (25-50 nM/kg, 150 μL, i.v.) increases arterial blood pressure in rats[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Chicks[1]
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Dosage:3.0, 7.0 or 15 nmol
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Administration:Intracerebroventrical injection (ICV) injection
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Result:Decreased food intake.
Increased number of c-Fos reactive cells in the paraventricular nucleus.
化学情報
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CAS 番号 88280-21-1
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分子量 643.82
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分子式 C32H53N9O5
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シーケンスの短縮
LPLRF-NH2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Scheel A, et al. LPLRFamide exerts short-term anorexigenic effects that coincide with magnocellular division of the hypothalamic paraventricular nucleus activation. Gen Comp Endocrinol. 2017 May 15;246:116-119. [Content Brief]
[2]. Barnard CS, et al. Increases in arterial blood pressure in the rat in response to a new vertebrate neuropeptide, LPLRFamide, and a related molluscan peptide, FMRFamide. Regul Pept. 1984 Apr;8(3):209-15. [Content Brief]
[3]. Chartrel N, et al. Structure and functions of the novel hypothalamic RFamide neuropeptides R-RFa and 26RFa in vertebrates. Peptides. 2006 May;27(5):1110-20. [Content Brief]
[4]. Hinuma S, et al. New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat Cell Biol. 2000 Oct;2(10):703-8. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
LPLRF-NH2 関連分類
HY-P3593 関連分類
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