Lyxose
Lyxose is a pentose carbohydrate that serves both as a precursor for synthesizing UDP-galactopyranose mutase inhibitors in tuberculosis research and as an inhibitor of hSGLT5-mediated mannose uptake. The content of Lyxose in the cecum of mice fed a Western-style diet decreases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 65-42-9
- 分子式: C5H10O5
- 分子量:150.13
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
D-lyxose (100 mM; 30 min) acts as a low-affinity competitive inhibitor of hSGLT5-mediated mannose transport in T-Rex HEK-293 cells, with 100 mM inhibiting 50% of uptake and an estimated Ki of ≥100 mM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 65-42-9
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分子量 150.13
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分子式 C5H10O5
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SMILES
OC[C@@H](O)[C@H](O)[C@H](O)C=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Ghezzi C, et al. Fingerprints of hSGLT5 sugar and cation selectivity. Am J Physiol Cell Physiol. 2014;306(9):C864-C870. [Content Brief]
[2]. Jena PK, et al. Intestinal Microbiota Remodeling Protects Mice from Western Diet-Induced Brain Inflammation and Cognitive Decline. Cells. 2022;11(3):504. Published 2022 Feb 1. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Lyxose 関連分類
HY-128753A 関連分類
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