Methimazole-d3
Based on 1 Customer Validation
Methimazole-d3 is a deuterium labeled Methimazole (HY-B0208). Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.00%
- CAS 番号: 1160932-07-9
- 分子式: C4H3D3N2S
- 分子量:117.19
-
保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
-
CAS 番号 1160932-07-9
-
非標識Cas 60-56-0
-
性状 Solid
-
分子量 117.19
-
分子式 C4H3D3N2S
-
Color White to off-white
-
SMILES
S=C1NC=CN1C([2H])([2H])[2H]
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (853.32 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : ≥ 50 mg/mL (426.66 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (276 KB)
-
SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 8.5332 mL | 42.6658 mL | 85.3315 mL | 213.3288 mL |
| 5 mM | 1.7066 mL | 8.5332 mL | 17.0663 mL | 42.6658 mL | |
| 10 mM | 0.8533 mL | 4.2666 mL | 8.5332 mL | 21.3329 mL | |
| 15 mM | 0.5689 mL | 2.8444 mL | 5.6888 mL | 14.2219 mL | |
| 20 mM | 0.4267 mL | 2.1333 mL | 4.2666 mL | 10.6664 mL | |
| 25 mM | 0.3413 mL | 1.7066 mL | 3.4133 mL | 8.5332 mL | |
| 30 mM | 0.2844 mL | 1.4222 mL | 2.8444 mL | 7.1110 mL | |
| 40 mM | 0.2133 mL | 1.0666 mL | 2.1333 mL | 5.3332 mL | |
| 50 mM | 0.1707 mL | 0.8533 mL | 1.7066 mL | 4.2666 mL | |
| 60 mM | 0.1422 mL | 0.7111 mL | 1.4222 mL | 3.5555 mL | |
| 80 mM | 0.1067 mL | 0.5333 mL | 1.0666 mL | 2.6666 mL | |
| 100 mM | 0.0853 mL | 0.4267 mL | 0.8533 mL | 2.1333 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.