Multitarget AD-IN-5
Multitarget AD-IN-5 (Compound 20), 9-Aminoacridine (HY-B1422) derivative, is a neuroprotective agent. Multitarget AD-IN-5 shows IC50 values of 0.614, 0.448, 3.73 and 1.55 μM for hAChE, hBChE, hMAO-A and hMAO-B. Multitarget AD-IN-5 can reduce length and diameter of Aβ42 fibers, and decrease the number of fibers per unit area. Multitarget AD-IN-5 can be used for research of Alzheimer's disease.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C21H15Cl3N2O
- 分子量:417.72
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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hAChE 0.614 μM (IC50) |
hBCHE 0.448 μM (IC50) |
hMAO-A 3.73 μM (IC50) |
hMAO-B 1.55 μM (IC50) |
Multitarget AD-IN-5 shows a CC50 of 95 μM for SH-SY5Ycells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 417.72
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分子式 C21H15Cl3N2O
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SMILES
COC1=CC2=C(NCC3=CC=C(Cl)C(Cl)=C3)C4=CC=C(Cl)C=C4N=C2C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Multitarget AD-IN-5 関連分類
HY-181041 関連分類
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