Mycro2
Based on 1 Customer Validation
Mycro2 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 23 μM for the inhibition of Myc/Max DNA binding activity. Mycro2 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.81%
- CAS 番号: 314049-21-3
- 分子式: C17H11F3N4OS2
- 分子量:408.42
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Anti-Prostate Cancer Compound Library
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Cancer Stem Cells Compound Library
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Mitochondrial Protection Compound Library
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Anti-Ovarian Cancer Compound Library
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
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Bioactive Compound Library
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Cell Proliferation Compound Library
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Lactic Acid Metabolic Compound Library
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High-Throughput Bioactive Compound Library
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生物活性
Mycro2 (10 or 20 μM, 7 days) can inhibit the proliferation of C-Myc-dependent cell lines U-2OS, MCF-7, Raji and NIH/3T3, but does not inhibit the proliferation of C-Myc-independent cancer cell line PC-12. Mycro2 significantly inhibits c-myc-induced gene transcription at 10 μM and selectively reduces unanchored growth of c-myc-transformed Rat1a cells at 20 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 314049-21-3
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性状 Solid
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分子量 408.42
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分子式 C17H11F3N4OS2
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Color Light yellow to yellow
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SMILES
O=C(C1=NN2C(C(F)(F)F)=CC(C3=CC=CS3)=NC2=C1)NCC4=CC=CS4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (306.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4485 mL | 12.2423 mL | 24.4846 mL | 61.2115 mL |
| 5 mM | 0.4897 mL | 2.4485 mL | 4.8969 mL | 12.2423 mL | |
| 10 mM | 0.2448 mL | 1.2242 mL | 2.4485 mL | 6.1211 mL | |
| 15 mM | 0.1632 mL | 0.8162 mL | 1.6323 mL | 4.0808 mL | |
| 20 mM | 0.1224 mL | 0.6121 mL | 1.2242 mL | 3.0606 mL | |
| 25 mM | 0.0979 mL | 0.4897 mL | 0.9794 mL | 2.4485 mL | |
| 30 mM | 0.0816 mL | 0.4081 mL | 0.8162 mL | 2.0404 mL | |
| 40 mM | 0.0612 mL | 0.3061 mL | 0.6121 mL | 1.5303 mL | |
| 50 mM | 0.0490 mL | 0.2448 mL | 0.4897 mL | 1.2242 mL | |
| 60 mM | 0.0408 mL | 0.2040 mL | 0.4081 mL | 1.0202 mL | |
| 80 mM | 0.0306 mL | 0.1530 mL | 0.3061 mL | 0.7651 mL | |
| 100 mM | 0.0245 mL | 0.1224 mL | 0.2448 mL | 0.6121 mL |
Mycro2 関連分類
HY-126979 関連分類
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