NBD-10007
NBD-10007 is a CD4 agonist. NBD-10007 has anti-HIV-1 viral activity.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1375736-65-4
- 分子式: C20H25ClN4O3S
- 分子量:436.96
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT2 | CC50 |
>62 μM
Compound: 9, NBD-10007, diastereoisomeric mixture
|
Cytotoxicity against human MT2 cells after 4 days by XTT assay
Cytotoxicity against human MT2 cells after 4 days by XTT assay
|
[PMID: 22524483] |
| MT2 | IC50 |
4.2 μM
Compound: 9, NBD-10007, diastereoisomeric mixture
|
Inhibition of X4-tropic HIV1 3B gp120-mediated entry into human MT2 cells assessed as Inhibition of p24 production incubated overnight followed by compound wash-out measured after 4 days post-infection by multi-cycle neutralization assay
Inhibition of X4-tropic HIV1 3B gp120-mediated entry into human MT2 cells assessed as Inhibition of p24 production incubated overnight followed by compound wash-out measured after 4 days post-infection by multi-cycle neutralization assay
|
[PMID: 22524483] |
化学情報
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CAS 番号 1375736-65-4
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分子量 436.96
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分子式 C20H25ClN4O3S
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SMILES
O=C(C(NC(C1NCCCC1)C2=NC(C)=C(CCO)S2)=O)NC3=CC=C(C=C3)Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)