Nipradolol
Nipradolol (KT-210; K-351) is a potent blocker of alpha-1-adrenergic receptors. Nipradolol inhibits the increase of intraocular pressure (IOP) in an albino rabbit model induced by Phenylephrine (HY-B0769). Nipradolo suppresses the noradrenaline (NA)-induced muscles contraction, also exhibits vasodilator activity on the dog coronary artery.
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- CAS 番号: 81486-22-8
- 分子式: C15H22N2O6
- 分子量:326.34
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Adrenergic Receptor アイソフォーム固有の製品をすべて表示
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生物活性
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α1-adrenergic receptor |
Nipradolol (1 μM; 10 min) inhibits K-induced contraction in dog muscles with an ID50 value of 0.8 μM[1].
Nipradolol (1 μM; 10 min) reduces the resting tone and to suppress the NA-induced contraction in proximal region[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 81486-22-8
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分子量 326.34
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分子式 C15H22N2O6
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SMILES
CC(C)NCC(O)COC1=C2C(CC(O[N+]([O-])=O)CO2)=CC=C1
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別名
KT 210; K 351; Hypadil
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Nipradolol 関連分類
HY-106523 関連分類
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