Norcaesalpinin E
Based on 1 Customer Validation
Norcaesalpinin E, a C-17-norcassane-type diterpene found in Caesalpinia crista, is a Plasmodium falciparum growth inhibitor with an IC50 of 90 nM. Norcaesalpinin E induces dose-dependent growth inhibition of Plasmodium falciparum. Norcaesalpinin E can be used for the research of malaria.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 93%
- CAS 番号: 854038-96-3
- 分子式: C21H28O6
- 分子量:376.44
-
保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Parasite アイソフォーム固有の製品をすべて表示
More
生物活性
|
Plasmodium 90 nM (IC50) |
Norcaesalpinin E (72 h) potently inhibits the growth of Plasmodium falciparum FCR-3/A2 clone in vitro with an IC50 of 90 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 854038-96-3
-
性状 Solid
-
分子量 376.44
-
分子式 C21H28O6
-
Color White to off-white
-
SMILES
C[C@@]([C@@](C[C@@H]1O)(C2(C)C)O)([C@H](CC2)OC(C)=O)[C@](CC3=C4C=CO3)([H])[C@]1([H])C4=O
-
Structure Classification
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
-
データシート (286 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Kalauni SK, et al. Antimalarial activity of cassane- and norcassane-type diterpenes from Caesalpinia crista and their structure-activity relationship. Biol Pharm Bull. 2006;29(5):1050-1052. [Content Brief]
[2]. Linn TZ, et al. Cassane- and norcassane-type diterpenes from Caesalpinia crista of Indonesia and their antimalarial activity against the growth of Plasmodium falciparum. J Nat Prod. 2005;68(5):706-710. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)