NPD9948
NPD9948 is an antitussive agent with antitussive activity in a guinea pig antitussive test. Its half antitussive dose (AtD50) is 14.5 mg/kg and 22.6 mg/kg when injected intraperitoneally and orally, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 59856-85-8
- 分子式: C13H14N6
- 分子量:254.29
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | IC50 |
100 nM
Compound: NPD9948
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Inhibition of DsRed-fused MTH1 (unknown origin) expressed in HEK293T cells using 8-oxo-dGTP as substrate
Inhibition of DsRed-fused MTH1 (unknown origin) expressed in HEK293T cells using 8-oxo-dGTP as substrate
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[PMID: 28280261] |
| HeLa | EC50 |
35 μM
Compound: NPD9948
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Cytotoxicity against human HeLa cells after 72 hrs by WST-8 assay
Cytotoxicity against human HeLa cells after 72 hrs by WST-8 assay
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[PMID: 28929756] |
化学情報
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CAS 番号 59856-85-8
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分子量 254.29
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分子式 C13H14N6
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SMILES
NC(N=C1NCCC2=CC=CC=C2)=NC3=C1NC=N3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
NPD9948 関連分類
HY-114723 関連分類
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