NSC114126
NSC114126 is a potent and orally active inhibitor of EGFR tyrosine kinase (EGFR-TK). NSC114126 has strong antiproliferative activities. NSC114126 has the potential for the research of cancer diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 24909-18-0
- 分子式: C22H20O4
- 分子量:348.39
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
EGFR アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
17.71 μM
Compound: NSC114126
|
Antiproliferative activity against human A-431 cells overexpressing EGFR assessed as cell growth inhibition by MTT assay
Antiproliferative activity against human A-431 cells overexpressing EGFR assessed as cell growth inhibition by MTT assay
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[PMID: 34995690] |
| HeLa | IC50 |
17.28 μM
Compound: NSC114126
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Antiproliferative activity against human HeLa cells assessed as cell growth inhibition by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition by MTT assay
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[PMID: 34995690] |
化学情報
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CAS 番号 24909-18-0
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分子量 348.39
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分子式 C22H20O4
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SMILES
O=C1C(C2=CC=C(CC)C=C2)=C(O)C(C(C3=CC=C(CC)C=C3)=C1O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
NSC114126 関連分類
HY-144445 関連分類
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