NSC49652
Based on 1 Customer Validation
NSC49652 is a reversible, orally active p75 neurotrophin receptor (p75NTR, also known as NGFR, TNFRSF16, and CD271) agonist. NSC49652 targets the transmembrane domain of p75NTR. NSC49652 induces apoptosis and affects the viability of melanoma cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.74%
- CAS 番号: 908563-68-8
- 分子式: C14H11NO2
- 分子量:225.24
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
p75NTR, Apoptosis[1]
化学情報
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CAS 番号 908563-68-8
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性状 Solid
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分子量 225.24
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分子式 C14H11NO2
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Color Light yellow to yellow
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SMILES
O=C(C1=CC=CC=C1O)/C=C/C2=CC=CN=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : ≥ 20.83 mg/mL (92.48 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4397 mL | 22.1985 mL | 44.3971 mL | 110.9927 mL |
| 5 mM | 0.8879 mL | 4.4397 mL | 8.8794 mL | 22.1985 mL | |
| 10 mM | 0.4440 mL | 2.2199 mL | 4.4397 mL | 11.0993 mL | |
| 15 mM | 0.2960 mL | 1.4799 mL | 2.9598 mL | 7.3995 mL | |
| 20 mM | 0.2220 mL | 1.1099 mL | 2.2199 mL | 5.5496 mL | |
| 25 mM | 0.1776 mL | 0.8879 mL | 1.7759 mL | 4.4397 mL | |
| 30 mM | 0.1480 mL | 0.7400 mL | 1.4799 mL | 3.6998 mL | |
| 40 mM | 0.1110 mL | 0.5550 mL | 1.1099 mL | 2.7748 mL | |
| 50 mM | 0.0888 mL | 0.4440 mL | 0.8879 mL | 2.2199 mL | |
| 60 mM | 0.0740 mL | 0.3700 mL | 0.7400 mL | 1.8499 mL | |
| 80 mM | 0.0555 mL | 0.2775 mL | 0.5550 mL | 1.3874 mL |