PROTAC STAT6 degrader-3
PROTAC STAT6 degrader-3 is a potent STAT6 PROTAC degrader with a DC50 of less than 1 nM. PROTAC STAT6 degrader-3 can be used for research on allergic/inflammatory diseases and cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3077385-98-6
- 分子式: C44H45F4N9O5
- 分子量:855.88
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
製品説明
体外実験
化学情報
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CAS 番号 3077385-98-6
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性状 Solid
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分子量 855.88
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分子式 C44H45F4N9O5
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Color White to off-white
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SMILES
O=C(N(C)C)C(N1)=CC2=C1C(F)=C(C3=CCCN(C(CCN4N=CC=C4)=O)C3)C=C2C5=C(F)C(F)=C(N6CCN(C7=C(F)C=C(NC8CCC(NC8=O)=O)C(OC)=C7)CC6)C=C5
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (58.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1684 mL | 5.8419 mL | 11.6839 mL | 29.2097 mL |
| 5 mM | 0.2337 mL | 1.1684 mL | 2.3368 mL | 5.8419 mL | |
| 10 mM | 0.1168 mL | 0.5842 mL | 1.1684 mL | 2.9210 mL | |
| 15 mM | 0.0779 mL | 0.3895 mL | 0.7789 mL | 1.9473 mL | |
| 20 mM | 0.0584 mL | 0.2921 mL | 0.5842 mL | 1.4605 mL | |
| 25 mM | 0.0467 mL | 0.2337 mL | 0.4674 mL | 1.1684 mL | |
| 30 mM | 0.0389 mL | 0.1947 mL | 0.3895 mL | 0.9737 mL | |
| 40 mM | 0.0292 mL | 0.1460 mL | 0.2921 mL | 0.7302 mL | |
| 50 mM | 0.0234 mL | 0.1168 mL | 0.2337 mL | 0.5842 mL |