PSB069
Based on 1 Customer Validation
PSB069 bearing a p-chlorophenylamino residue is a potent, well-tolerated and nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.5%
- CAS 番号: 78510-31-3
- 分子式: C20H12ClN2NaO5S
- 分子量:450.83
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
IC50 & Target
Ki: 16~18 μM (NTPDases1, 2, 3)[1]
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NG108-15 | IC50 |
20 μM
Compound: 16
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Antagonist activity at mouse P2Y2 receptor in mouse NG108-15 cells assessed as inhibition of UTP-induced calcium mobilization
Antagonist activity at mouse P2Y2 receptor in mouse NG108-15 cells assessed as inhibition of UTP-induced calcium mobilization
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[PMID: 18006312] |
体外実験
PSB069 is a nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 78510-31-3
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性状 Solid
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分子量 450.83
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分子式 C20H12ClN2NaO5S
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Color Pale purple to purple
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SMILES
O=S(C(C(N)=C1C2=O)=CC(NC3=CC=C(Cl)C=C3)=C1C(C4=C2C=CC=C4)=O)(O[Na])=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 45 mg/mL (99.82 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2181 mL | 11.0907 mL | 22.1813 mL | 55.4533 mL |
| 5 mM | 0.4436 mL | 2.2181 mL | 4.4363 mL | 11.0907 mL | |
| 10 mM | 0.2218 mL | 1.1091 mL | 2.2181 mL | 5.5453 mL | |
| 15 mM | 0.1479 mL | 0.7394 mL | 1.4788 mL | 3.6969 mL | |
| 20 mM | 0.1109 mL | 0.5545 mL | 1.1091 mL | 2.7727 mL | |
| 25 mM | 0.0887 mL | 0.4436 mL | 0.8873 mL | 2.2181 mL | |
| 30 mM | 0.0739 mL | 0.3697 mL | 0.7394 mL | 1.8484 mL | |
| 40 mM | 0.0555 mL | 0.2773 mL | 0.5545 mL | 1.3863 mL | |
| 50 mM | 0.0444 mL | 0.2218 mL | 0.4436 mL | 1.1091 mL | |
| 60 mM | 0.0370 mL | 0.1848 mL | 0.3697 mL | 0.9242 mL | |
| 80 mM | 0.0277 mL | 0.1386 mL | 0.2773 mL | 0.6932 mL |
PSB069 関連分類
HY-103262 関連分類
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