Pterin
Based on 1 Customer Validation
Pterin is a pteridine with antibacterial activity. Pterin binds to the Fe2+ active site via its carbonyl group, reducing the oxygen activation energy barrier in hydroxylases. Pterin participates in metabolic redox processes. Pterin can be used in research related to cancer, vitiligo, bacterial infections, phenylketonuria, Parkinson's disease, schizophrenia and depression.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.75%
- CAS 番号: 2236-60-4
- 分子式: C6H5N5O
- 分子量:163.14
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
Pterin (Ptr) generates superoxide anion and hydrogen peroxide when irradiated with UV-A in neutral or slightly acidic aqueous solutions, via a photoinduced electron transfer mechanism[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2236-60-4
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性状 Solid
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分子量 163.14
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分子式 C6H5N5O
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Color Brown to reddish brown
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SMILES
O=C1NC(N)=NC2=NC=CN=C12
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
TFA : 10 mg/mL (61.30 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
[2]. Mahendran R, et al. Evaluation of Pterin, a Promising Drug Candidate from Cyanide Degrading Bacteria. Current microbiology. 2018 Jun;75(6):684-693. [Content Brief]
[8]. Rutowski RL, et al. Pterin pigments amplify iridescent ultraviolet signal in males of the orange sulphur butterfly, Colias eurytheme. Proceedings. Biological sciences. 2005 Nov 07;272(1578):2329-35. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| TFA | 1 mM | 6.1297 mL | 30.6485 mL | 61.2970 mL | 153.2426 mL |
| 5 mM | 1.2259 mL | 6.1297 mL | 12.2594 mL | 30.6485 mL | |
| 10 mM | 0.6130 mL | 3.0649 mL | 6.1297 mL | 15.3243 mL | |
| 15 mM | 0.4086 mL | 2.0432 mL | 4.0865 mL | 10.2162 mL | |
| 20 mM | 0.3065 mL | 1.5324 mL | 3.0649 mL | 7.6621 mL | |
| 25 mM | 0.2452 mL | 1.2259 mL | 2.4519 mL | 6.1297 mL | |
| 30 mM | 0.2043 mL | 1.0216 mL | 2.0432 mL | 5.1081 mL | |
| 40 mM | 0.1532 mL | 0.7662 mL | 1.5324 mL | 3.8311 mL | |
| 50 mM | 0.1226 mL | 0.6130 mL | 1.2259 mL | 3.0649 mL | |
| 60 mM | 0.1022 mL | 0.5108 mL | 1.0216 mL | 2.5540 mL |