Randaiol
Randaiol is an antioxidant that can be isolated from the stem bark of Magnolia officinalis. Randaiol inhibits LPS-induced NO production and has anti-inflammatory and antioxidant activities.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 87562-14-9
- 分子式: C15H14O3
- 分子量:242.27
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
1.2 μg/mL
Compound: 6
|
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess reagent method
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess reagent method
|
[PMID: 19086868] |
| HCC827 | IC50 |
>40 μM
Compound: 13
|
Antiproliferative activity against human HCC827 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCC827 cells after 72 hrs by MTT assay
|
[PMID: 30006164] |
| HepG2 2.2.15 | CC50 |
200.57 μM
Compound: 8
|
Cytotoxicity against human HepG2(2.2.15) cells after 12 days by MTT assay
Cytotoxicity against human HepG2(2.2.15) cells after 12 days by MTT assay
|
[PMID: 23434030] |
| HepG2 2.2.15 | IC50 |
162.43 μM
Compound: 8
|
Antiviral activity against Hepatitis B virus infected in human HepG2.2.15 cells assessed as inhibition of HBsAg secretion after 12 days by ELISA
Antiviral activity against Hepatitis B virus infected in human HepG2.2.15 cells assessed as inhibition of HBsAg secretion after 12 days by ELISA
|
[PMID: 23434030] |
| HepG2 2.2.15 | IC50 |
30.24 μM
Compound: 8
|
Antiviral activity against Hepatitis B virus infected in human HepG2.2.15 cells assessed as inhibition of HBeAg secretion after 12 days by ELISA
Antiviral activity against Hepatitis B virus infected in human HepG2.2.15 cells assessed as inhibition of HBeAg secretion after 12 days by ELISA
|
[PMID: 23434030] |
| HepG2 2.2.15 | IC50 |
>1000 μM
Compound: 8
|
Antiviral activity against Hepatitis B virus infected in human HepG2.2.15 cells assessed as inhibition of HBV DNA replication after 72 hrs by PCR analysis
Antiviral activity against Hepatitis B virus infected in human HepG2.2.15 cells assessed as inhibition of HBV DNA replication after 72 hrs by PCR analysis
|
[PMID: 23434030] |
| NCI-H1975 | IC50 |
>40 μM
Compound: 13
|
Antiproliferative activity against human NCI-H1975 cells after 72 hrs by MTT assay
Antiproliferative activity against human NCI-H1975 cells after 72 hrs by MTT assay
|
[PMID: 30006164] |
| NCI-H460 | IC50 |
>40 μM
Compound: 13
|
Antiproliferative activity against human H460 cells after 72 hrs by MTT assay
Antiproliferative activity against human H460 cells after 72 hrs by MTT assay
|
[PMID: 30006164] |
化学情報
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CAS 番号 87562-14-9
-
分子量 242.27
-
分子式 C15H14O3
-
SMILES
OC1=CC=C(O)C=C1C2=CC(CC=C)=CC=C2O
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別名
Magnotriol A
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)