Rapamycin dialdehyde
Rapamycin dialdehyde is a non-immunosuppressive macrolide dialdehyde that promotes neuronal regeneration and functional recovery by inducing neurite outgrowth, and inhibits solid tumor cell growth and hyperproliferative vascular diseases. Rapamycin dialdehyde is used in the research of neurodegenerative diseases and cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 500733-49-3
- 分子式: C51H79NO15
- 分子量:946.17
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 3T3 | IC50 |
0.72 μg/mL
|
Antineoplastic activity against mouse 3T3 ovarian tumor cells assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
Antineoplastic activity against mouse 3T3 ovarian tumor cells assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
|
en?oq=WO+03%2f018574+Al |
| 3T3 | IC50 |
0.68 μg/mL
|
Antineoplastic activity against mouse 3T3/H2N ovarian tumor cells resistant to cis-platin assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
Antineoplastic activity against mouse 3T3/H2N ovarian tumor cells resistant to cis-platin assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
|
en?oq=WO+03%2f018574+Al |
| A-431 | IC50 |
0.91 μg/mL
|
Antineoplastic activity against human A431 vulva epidermoid tumor cells assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
Antineoplastic activity against human A431 vulva epidermoid tumor cells assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
|
en?oq=WO+03%2f018574+Al |
| SK-BR-3 | IC50 |
0.52 μg/mL
|
Antineoplastic activity against human SKBR3 breast tumor cells assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
Antineoplastic activity against human SKBR3 breast tumor cells assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
|
en?oq=WO+03%2f018574+Al |
| MDA-MB-435 | IC50 |
1.23 μg/mL
|
Antineoplastic activity against human MDA-435 breast tumor cells assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
Antineoplastic activity against human MDA-435 breast tumor cells assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
|
en?oq=WO+03%2f018574+Al |
| SW-620 | IC50 |
1.41 μg/mL
|
Antineoplastic activity against human SW620 colon tumor cells assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
Antineoplastic activity against human SW620 colon tumor cells assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B colorimetric assay.
|
en?oq=WO+03%2f018574+Al |
体外実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
- PC12 NGF-Induced Neuronal Differentiation Culture
- SH-SY5Y Neuronal Differentiation Culture
- Protocol for Cell Counting and Cell Density Analysis
- Somatic Cell Culture
- SH-SY5Y neuronal-like differentiation
- Cell differentiation
- CCK-8/WST-8 Cell Proliferation Assay
- PC12 NGF-induced neuronal-like differentiation
- Cell Counting-Based Growth Curve Assay
- MTT Cell Proliferation Assay
- Cell Viability Determination by MTT Colorimetric Assay
化学情報
-
CAS 番号 500733-49-3
-
分子量 946.17
-
分子式 C51H79NO15
-
SMILES
O=C([C@@]1(O[C@@H](CC[C@H]1C)C[C@H](OC)/C(C)=C/C=O)O)C(N2[C@@H](CCCC2)C(O[C@@H](CC([C@H](C)/C=C(C)/[C@@H](O)[C@@H](OC)C([C@H](C)C[C@H](C)/C=C/C=O)=O)=O)[C@H](C)C[C@H]3C[C@H]([C@@H](CC3)O)OC)=O)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Rapamycin dialdehyde 関連分類
HY-W746425 関連分類
Powered by Bioz
Keywords
- Rapamycin dialdehyde
- 500733-49-3
- Biochemical Assay Reagents
- restenosis
- neurite outgrowth
- SH-SY5Y cells
- macrolide dialdehyde
- neurodegenerative disorders
- 3T3
- SKBR3
- solid tumor cell growth
- tumor cell growth
- neuronal regeneration
- MDA-435
- 3T3/H2N
- A431
- SW620
- hyperproliferative vascular diseases
- cancer
- Inhibitor
- inhibitor
- inhibit