Saccharic acid
Based on 1 Customer Validation
Saccharic acid is a competitive and potent inhibitor of β-glucuronidase. Saccharic acid inhibits glucuronide synthesis. Saccharic acid as an efficient iron chelate to enhance photo-Fenton
degradation of organic contaminants.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.73%
- CAS 番号: 87-73-0
- 分子式: C6H10O8
- 分子量:210.14
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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生物活性
degradation of organic contaminants[2].
Saccharic acid (50 µM Fe (III)-saccharic acid90 min UV-C irradiation) enhances photo-Fenton degradation of methylene blue[1].
Saccharic acid (50-150 x 10-4 M; 1 h) potently, competitively, and reversibly inhibits β-glucuronidase activity from mouse liver and mouse kidney[2].
Saccharic acid (1×10-3 M; 2 h) strongly inhibits hydrolysis of o-aminophenylglucuronide by mouse liver β-glucuronidase preparations[2].
Saccharic acid (0.01 M; 90 min) reduces β-glucuronidase activity in intact mouse liver slices[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Saccharic acid (2 g/kg; intraperitoneal injection; daily; 3 weeks) or (3%; dietary supplementation; ad libitum; 3 weeks) does not alter normal growth in infant mice[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Infant mice[2]
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Dosage:2 g/kg (injection); 3% (dietary)
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Administration:intraperitoneal injection; daily; 3 weeks; dietary supplementation; ad libitum; 3 weeks
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Result:Showed no effect on normal growth, with animal weights identical to control values.
化学情報
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CAS 番号 87-73-0
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性状 Solid
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分子量 210.14
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分子式 C6H10O8
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Color White to off-white
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SMILES
[C@H]([C@@H]([C@H](C(=O)O)O)O)([C@@H](C(=O)O)O)O
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
H2O : 250 mg/mL (1189.68 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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取扱説明書 (2659 KB)
参考文献
[1]. Subramanian G, et al. Introducing saccharic acid as an efficient iron chelate to enhance photo-Fenton degradation of organic contaminants. Water Res. 2016;104:168-177. [Content Brief]
[2]. Karunairatnam M C, et al. The inhibition of β-glucuronidase by saccharic acid and the role of the enzyme in glucuronide synthesis[J]. Biochemical Journal, 1949, 44(5): 599. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.7587 mL | 23.7937 mL | 47.5873 mL | 118.9683 mL |
| 5 mM | 0.9517 mL | 4.7587 mL | 9.5175 mL | 23.7937 mL | |
| 10 mM | 0.4759 mL | 2.3794 mL | 4.7587 mL | 11.8968 mL | |
| 15 mM | 0.3172 mL | 1.5862 mL | 3.1725 mL | 7.9312 mL | |
| 20 mM | 0.2379 mL | 1.1897 mL | 2.3794 mL | 5.9484 mL | |
| 25 mM | 0.1903 mL | 0.9517 mL | 1.9035 mL | 4.7587 mL | |
| 30 mM | 0.1586 mL | 0.7931 mL | 1.5862 mL | 3.9656 mL | |
| 40 mM | 0.1190 mL | 0.5948 mL | 1.1897 mL | 2.9742 mL | |
| 50 mM | 0.0952 mL | 0.4759 mL | 0.9517 mL | 2.3794 mL | |
| 60 mM | 0.0793 mL | 0.3966 mL | 0.7931 mL | 1.9828 mL | |
| 80 mM | 0.0595 mL | 0.2974 mL | 0.5948 mL | 1.4871 mL | |
| 100 mM | 0.0476 mL | 0.2379 mL | 0.4759 mL | 1.1897 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Saccharic acid 関連分類
HY-W345885 関連分類
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