(rel)-Salcolin A
(rel)-Salcolin A is a flavonoid lignan compound with anticancer, anti-inflammatory, and neuroprotective activities. (rel)-Salcolin A has IC50 values ??of 66.69 μM and 56.12 μM against anaplastic thyroid carcinoma cells (HTH83) and papillary thyroid carcinoma cells (TPC1), respectively. (rel)-Salcolin A also inhibits LPS-induced NO production with an IC50 of 14.65 μM. (rel)-Salcolin A exerts its effects by inducing necroptosis in thyroid cancer cells, inhibiting the production of the inflammatory factor NO, and protecting against glutamate-induced neuronal cell damage, with a neuroprotective E50 of 47.44 μM. (rel)-Salcolin A can be used in research related to thyroid cancer, anti-inflammation, and neuroprotection. (rel)-Salcolin A can be naturally extracted from the leaves of Casearia arborea and the stems of Zea mays (corn).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1977557-69-9
- 分子式: C27H26O11
- 分子量:526.49
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
化学情報
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CAS 番号 1977557-69-9
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分子量 526.49
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分子式 C27H26O11
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SMILES
O=C1C2=C(O)C=C(O)C=C2OC(C3=CC(OC)=C(C(OC)=C3)O[C@H](CO)[C@@H](C4=CC(OC)=C(C=C4)O)O)=C1
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Jung YJ, et al. Lignan and flavonoids from the stems of Zea mays and their anti-inflammatory and neuroprotective activities. Arch Pharm Res. 2015 Feb;38(2):178-85. [Content Brief]
[2]. Santos AL, et al. Exploring the Antiproliferative Activity of Flavolignans From the Leaves of Casearia arborea (Salicaceae). Chem Biodivers. 2025 Dec;22(12):e01489. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
(rel)-Salcolin A 関連分類
HY-N16764 関連分類
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