SC-50605
SC-50605 and SC-51146 are second-generation leukotriene B4 (LTB4) receptor antagonists that effectively inhibit LTB4-induced chemotaxis in guinea pigs. SC-50605 targets the LTB4 receptor and has the potential to inhibit inflammatory diseases such as asthma, rheumatoid arthritis, and skin diseases..
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 138828-39-4
- 分子式: C30H35NO6S
- 分子量:537.67
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Leukotriene Receptor アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
LTB4[1]
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
660 nM
Compound: 35
|
Inhibitory activity against LTB4 production in HL60s.
Inhibitory activity against LTB4 production in HL60s.
|
[PMID: 7699700] |
| HL-60 | IC50 |
928 nM
Compound: 35
|
Inhibitory activity against PGE-2 production in HL60s.
Inhibitory activity against PGE-2 production in HL60s.
|
[PMID: 7699700] |
化学情報
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CAS 番号 138828-39-4
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分子量 537.67
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分子式 C30H35NO6S
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SMILES
O=C(O)C1CCC2=CC=C(C(CCC)=C2O1)OCCCOC3=CC=C(C(OC)=C3CC4CC4)C5=CSC=N5
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)