Tamtuvetmab
Based on 1 Customer Validation
Tamtuvetmab (AT-005) is a caninised blontuvetmab against CD52. Tamtuvetmab increases progression-free survival (PFS), exhibits in vivo efficacy in dogs with naïve T-cell lymphoma (LSA). Tamtuvetmab has been approved by veterinary.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97%
- CAS 番号: 1608122-71-9
- 分子量:146.346 kDa
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Caninized IgG2 Vkappa Clambda
Caninized
Canlupfam CD52
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:T-cell LSA Model in Dog[1]
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Dosage:5 mg/mL, 7.5-30 mL; Dogs weighing for 2-15 kg received 7.5 mL, for 15.1-30 kg received 15 mL, for 30.1-45 kg received 22.5 mL, for 45.1-60 kg received 30 mL
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Administration:Intravenous injection; 15-30 min
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Result:Showed in vivo efficacy with severe side effect.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG2-Vkappa-Clambda
ELISA, FACS, Functional assay
化学情報
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CAS 番号 1608122-71-9
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性状 Liquid
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分子量 146.346 kDa
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Color Colorless to light yellow
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SMILES
[Tamtuvetmab]
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別名
AT-005
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輸送条件
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (257 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
参考文献
[1]. Musser ML, et al. Randomised trial evaluating chemotherapy alone or chemotherapy and a novel monoclonal antibody for canine T-cell lymphoma: A multicentre US study. Vet Rec Open. 2022 Nov 1;9(1):e49. [Content Brief]
[2]. Rhodes L. Changing innovation into a registered product: From concept to regulatory approval. Theriogenology. 2018 May;112:75-81. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)