TL13-22
Based on 1 Customer Validation
TL13-22 is a negative control for TL13-12 (HY-122582) and a potent ALK inhibitor with an IC50 of 0.54 nM. TL13-22 does not degrade ALK in cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.71%
- CAS 番号: 2229036-65-9
- 分子式: C45H55ClN10O9S
- 分子量:947.50
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Kinase Inhibitor Library
HY-L009
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Protein Tyrosine Kinase Compound Library
HY-L016
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Anti-Cancer Compound Library
HY-L025
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Heterocyclic Compound Library
HY-L138
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Membrane Protein-targeted Compound Library
HY-L149
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Serine/Threonine Kinase Inhibitor Library
HY-L164
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Anti-Brain Cancer Compound Library
HY-L188
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
生物活性
IC50: 0.54 nM (ALK)[1]
化学情報
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CAS 番号 2229036-65-9
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性状 Solid
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分子量 947.50
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分子式 C45H55ClN10O9S
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Color Light yellow to yellow
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SMILES
O=C(NCCOCCOCCN1CCN(C2=CC=C(NC3=NC=C(Cl)C(NC4=CC=CC=C4S(=O)(C(C)C)=O)=N3)C(OC)=C2)CC1)CNC5=CC=CC(C(N6C7C(NCCC7)=O)=O)=C5C6=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 250 mg/mL (263.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0554 mL | 5.2770 mL | 10.5541 mL | 26.3852 mL |
| 5 mM | 0.2111 mL | 1.0554 mL | 2.1108 mL | 5.2770 mL | |
| 10 mM | 0.1055 mL | 0.5277 mL | 1.0554 mL | 2.6385 mL | |
| 15 mM | 0.0704 mL | 0.3518 mL | 0.7036 mL | 1.7590 mL | |
| 20 mM | 0.0528 mL | 0.2639 mL | 0.5277 mL | 1.3193 mL | |
| 25 mM | 0.0422 mL | 0.2111 mL | 0.4222 mL | 1.0554 mL | |
| 30 mM | 0.0352 mL | 0.1759 mL | 0.3518 mL | 0.8795 mL | |
| 40 mM | 0.0264 mL | 0.1319 mL | 0.2639 mL | 0.6596 mL | |
| 50 mM | 0.0211 mL | 0.1055 mL | 0.2111 mL | 0.5277 mL | |
| 60 mM | 0.0176 mL | 0.0880 mL | 0.1759 mL | 0.4398 mL | |
| 80 mM | 0.0132 mL | 0.0660 mL | 0.1319 mL | 0.3298 mL | |
| 100 mM | 0.0106 mL | 0.0528 mL | 0.1055 mL | 0.2639 mL |
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