UBP296
UBP296 is a potent and selective antagonist of GLUK5-containing kainate receptor in the spinal cord. UBP296 reversibly blocks ATPA-induced depressions of synaptic transmission, and affects AMPA receptor-mediated synaptic transmission directly in rat hippocampal slices.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 745055-86-1
- 分子式: C15H15N3O6
- 分子量:333.30
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-107602
UBP310Selective GluR5 Antagonist -
HY-107604
UBP 302iGluR Antagonist -
HY-N2309
Kainic acidNeuroexcitatory Amino Acid Agonist -
HY-101261
ATPAGluR5 Activator -
HY-107602R
UBP310 (Standard)Reference Standard -
HY-107606
UBP301Kainate Receptor Antagonist -
HY-107601
UBP316GluK1/GluR5 Antagonist -
HY-100837
5-IodowillardiineKainate Receptor Agonist -
HY-107603
NS3763GLUK5 Receptor Antagonist
iGluR アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
IC50: 3.5 ± 1.5 μM (GLUK5), 4.0 ± 0.7 μM (GLUK5/GLUK6), 7.0 ± 5.1 μM (GLUK5/GLUK2)[1]
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
880 μM
Compound: 38a
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Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cells
Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cells
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[PMID: 16302825] |
化学情報
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CAS 番号 745055-86-1
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分子量 333.30
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分子式 C15H15N3O6
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SMILES
O=C(N(C=CC1=O)CC(N)C(O)=O)N1CC2=C(C=CC=C2)C(O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
UBP296 関連分類
HY-107605 関連分類
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