Vitamin D3-d6
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Vitamin D3-d6 (Cholecalciferol-d6 ) is the deuterium labeled Vitamin D3 (HY-15398) . Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.47%
- CAS 番号: 118584-54-6
- 分子式: C27H38D6O
- 分子量:390.67
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保管条件:
-80°C, protect from light, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 118584-54-6
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非標識Cas 67-97-0
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性状 Solid
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分子量 390.67
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分子式 C27H38D6O
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Color White to light yellow
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SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C([2H])([2H])[2H])C([2H])([2H])[2H])([H])/C(CCC1)=C/C=C3C(CC[C@@H](C\3)O)=C
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別名
Cholecalciferol-d6; Colecalciferol-d6
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輸送条件
Shipping with dry ice.
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保管条件
-80°C, protect from light, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
溶剤 & 溶解度
DMSO : 66.67 mg/mL (170.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Nazik Al-Hashimi, et al. Cholecalciferol
[2]. Laura Bergadà, et al. Role of local bioactivation of vitamin D by CYP27A1 and CYP2R1 in the control of cell growth in normal endometrium and endometrial carcinoma. Lab Invest. 2014 Jun;94(6):608-22 [Content Brief]
[3]. Hiroki Yoshioka, et al. Vitamin D3-induced hypercalcemia increases carbon tetrachloride-induced hepatotoxicity through elevated oxidative stress in mice. PLoS One. 2017 Apr 27;12(4):e0176524. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5597 mL | 12.7985 mL | 25.5971 mL | 63.9926 mL |
| 5 mM | 0.5119 mL | 2.5597 mL | 5.1194 mL | 12.7985 mL | |
| 10 mM | 0.2560 mL | 1.2799 mL | 2.5597 mL | 6.3993 mL | |
| 15 mM | 0.1706 mL | 0.8532 mL | 1.7065 mL | 4.2662 mL | |
| 20 mM | 0.1280 mL | 0.6399 mL | 1.2799 mL | 3.1996 mL | |
| 25 mM | 0.1024 mL | 0.5119 mL | 1.0239 mL | 2.5597 mL | |
| 30 mM | 0.0853 mL | 0.4266 mL | 0.8532 mL | 2.1331 mL | |
| 40 mM | 0.0640 mL | 0.3200 mL | 0.6399 mL | 1.5998 mL | |
| 50 mM | 0.0512 mL | 0.2560 mL | 0.5119 mL | 1.2799 mL | |
| 60 mM | 0.0427 mL | 0.2133 mL | 0.4266 mL | 1.0665 mL | |
| 80 mM | 0.0320 mL | 0.1600 mL | 0.3200 mL | 0.7999 mL | |
| 100 mM | 0.0256 mL | 0.1280 mL | 0.2560 mL | 0.6399 mL |