WIN 62577
WIN 62577 is a species-selective tachykinin NK1 receptor antagonist. WIN 62577 is also an allosteric enhancer with micromolar potency at M3 receptors. WIN 62577 exhibits potent antiviral activity against SARS-CoV-2.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 138091-43-7
- 分子式: C29H31N3O
- 分子量:437.58
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
化学情報
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CAS 番号 138091-43-7
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分子量 437.58
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分子式 C29H31N3O
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SMILES
C[C@@]12[C@]3([H])[C@](CCC1=CC4=NC5=NC6=CC=CC=C6N5C=C4C2)([H])[C@@]7([H])[C@](CC3)([C@](O)(CC7)C#C)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Briejer MR, et, al. Substance P-induced contractions of the guinea-pig proximal colon through stimulation of post-junctional tachykinin NK1 receptors. Eur J Pharmacol. 1993 Nov 30;250(1):181-3. [Content Brief]
[2]. Lazareno S, et, al. Progress toward a high-affinity allosteric enhancer at muscarinic M1 receptors. J Mol Neurosci. 2003;20(3):363-7. [Content Brief]
[3]. Singh A, et, al. Structural and Mechanistic Insights into the Main Protease (Mpro) Dimer Interface Destabilization Inhibitor: Unveiling New Therapeutic Avenues against SARS-CoV-2. Biochemistry. 2025 Apr 1;64(7):1589-1605. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
WIN 62577 関連分類
HY-169501 関連分類
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