Z32439948
Z32439948 is a butyrylcholinesterase (BChE) inhibitor (IC50: 1.4 μM, hBChE) and is a derivative of m-sulfamoylbenzamide. Z32439948 also exhibited neuroprotective effects against glutamate in SH-SY5Y cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 920845-86-9
- 分子式: C25H26N4O4S
- 分子量:478.56
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
|
BChE 1.4 μM (IC50, [1]) |
体外実験
Z32439948 (1-5 μM; 48 h) has neuroprotective effects on glutamate (31 mM)-induced SH-SY5Y cell death[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:SH-SY5Y, BV2 cells
-
Concentration:1 μM, 2 μM, 5 μM
-
Incubation Time:48 h; with or without 31 mM Glutamate
-
Result:Protected cell from Glutamate induced damage.
化学情報
-
CAS 番号 920845-86-9
-
分子量 478.56
-
分子式 C25H26N4O4S
-
SMILES
O=C(NCCC1=CNC2=C1C=CC=C2)C3=CC=C(OC)C(S(NCCC4=NC=CC=C4)(=O)=O)=C3
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)