JY-3-094
Based on 1 Customer Validation
JY-3-094 is a Myc inhibitor that inhibits Myc-Max heterodimer formation (IC50: 33 μM).
For research use only. We do not sell to patients.
- Purity: 97.04%
- CAS No.: 389076-27-1
- Formula: C13H8N4O5
- Molecular Weight:300.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
IC50: 33 μM (Myc-Max)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Daudi | IC50 |
56 μM
Compound: 3q, JY-3-094
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Cytotoxicity against human Daudi cells assessed as growth inhibition after 3 to 5 days by MTT assay
Cytotoxicity against human Daudi cells assessed as growth inhibition after 3 to 5 days by MTT assay
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[PMID: 23177256] |
| HL-60 | IC50 |
184 μM
Compound: 3q, JY-3-094
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Cytotoxicity against human HL60 cells assessed as growth inhibition after 3 to 5 days by MTT assay
Cytotoxicity against human HL60 cells assessed as growth inhibition after 3 to 5 days by MTT assay
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[PMID: 23177256] |
| HL-60 | IC50 |
30 μM
Compound: JY-3-094
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Inhibition of cell development in human HL-60 cells
Inhibition of cell development in human HL-60 cells
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[PMID: 38340508] |
Chemical Information
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CAS No. 389076-27-1
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Appearance Solid
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Molecular Weight 300.23
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Formula C13H8N4O5
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Color Orange to red
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SMILES
O=C(O)C1=CC=C(NC2=CC=C([N+]([O-])=O)C3=NON=C32)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (83.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3308 mL | 16.6539 mL | 33.3078 mL | 83.2695 mL |
| 5 mM | 0.6662 mL | 3.3308 mL | 6.6616 mL | 16.6539 mL | |
| 10 mM | 0.3331 mL | 1.6654 mL | 3.3308 mL | 8.3269 mL | |
| 15 mM | 0.2221 mL | 1.1103 mL | 2.2205 mL | 5.5513 mL | |
| 20 mM | 0.1665 mL | 0.8327 mL | 1.6654 mL | 4.1635 mL | |
| 25 mM | 0.1332 mL | 0.6662 mL | 1.3323 mL | 3.3308 mL | |
| 30 mM | 0.1110 mL | 0.5551 mL | 1.1103 mL | 2.7756 mL | |
| 40 mM | 0.0833 mL | 0.4163 mL | 0.8327 mL | 2.0817 mL | |
| 50 mM | 0.0666 mL | 0.3331 mL | 0.6662 mL | 1.6654 mL | |
| 60 mM | 0.0555 mL | 0.2776 mL | 0.5551 mL | 1.3878 mL | |
| 80 mM | 0.0416 mL | 0.2082 mL | 0.4163 mL | 1.0409 mL |
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