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Fepixnebart

(Synonyms: LY-3016859)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Fepixnebart (LY3016859) is a humanized monoclonal hIgG4 antibody, which binds and neutralizes only TGFα and epiregulin with high affinity. Fepixnebart can be used for the study of diabetic nephropathy and broad-spectrum chronic pain, including diabetic peripheral neuropathic pain (DPNP), signs and symptoms of osteoarthritis (OA), and chronic low back pain (CLBP).

For research use only. We do not sell to patients.

  • Purity: 96.46%
  • CAS No.: 2489584-93-0
  • Molecular Weight:145.44 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Fepixnebart
  • Experimental Validation Results for Fepixnebart
  • Fepixnebart Chemical Structure
  • Experimental Validation Results for Fepixnebart
  • Experimental Validation Results for Fepixnebart
  • Fepixnebart Chemical Structure
    Fepixnebart Chemical Structure
CAS No.: 2489584-93-0
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Flow cytometric analysis of 1.5X106 Balb/3T3 cells with Fepixnebart (HY-P990071, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 (S228P) kappa, Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Fepixnebart Chemical Structure
    1/16
  • Fepixnebart
  • Flow cytometric analysis of 1.5X106 Balb/3T3 cells with Fepixnebart (HY-P990071, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 (S228P) kappa, Isotype Control (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).