5-OH-DPAT
5-OH-DPAT (5-Hydroxy-DPAT) is a potent and selective dopamine D2-receptor agonist lacking effects at 5-HT receptors. 5-OH-DPAT produces a moderate facilitation of the male rat sexual behavior.
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- CAS No.: 68593-96-4
- 화학식: C16H25NO
- 분자량:247.38
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Dopamine Receptor Isoforms
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Biological Activity
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D2 Receptor |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| AtT20 | EC50 |
1.23 nM
Compound: 5-OH-DPAT
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Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma binding
Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma binding
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[PMID: 20038106] |
Chemical Information
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CAS No. 68593-96-4
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분자량 247.38
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화학식 C16H25NO
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SMILES
OC1=CC=CC2=C1CCC(N(CCC)CCC)C2
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Synonyms
5-Hydroxy-DPAT
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Ahlenius S, et al. Evidence for selective inhibition of limbic forebrain dopamine synthesis by 8-OH-DPAT in the rat. Naunyn Schmiedebergs Arch Pharmacol. 1989 May;339(5):551-6. [Content Brief]
[2]. Karlsson A, et al. (R)- and (S)-5-hydroxy-2-(dipropylamino)tetralin (5-OH DPAT): assessment of optical purities and dopaminergic activities. Chirality. 1990;2(2):90-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-OH-DPAT Related Classifications
HY-131531A Related Classifications
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