6-Hydroxyindole (Standard)
6-Hydroxyindole (Standard) is the analytical standard of 6-Hydroxyindole (HY-W002438). This product is intended for research and analytical applications. 6-Hydroxyindole is an orally active, endogenous long-acting OATP1B1 inhibitor. 6-Hydroxyindole does not alter the cell surface expression or subcellular localization of OATP1B1. 6-Hydroxyindole protects cells against Ferroptosis. 6-Hydroxyindole possesses intrinsic radical-trapping antioxidant activity. 6-Hydroxyindole serves as a component of oxidative hair dyes. 6-Hydroxyindole can be used in research related to renal failure and neurodegenerative diseases.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2380-86-1
- 화학식: C8H7NO
- 분자량:133.15
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 2380-86-1
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분자량 133.15
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화학식 C8H7NO
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SMILES
OC1=CC2=C(C=C1)C=CN2
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Masuo Y, et al. 6-Hydroxyindole is an endogenous long-lasting OATP1B1 inhibitor elevated in renal failure patients. Drug Metab Pharmacokinet. 2020;35(6):555-562. [Content Brief]
[2]. Jakaria M, et al. The role of hydroxyindoles in protecting neuronal cultures from ferroptosis. Cell Death Discov. 2025;11(1):329. Published 2025 Jul 16. [Content Brief]
[3]. Burnett CL, et al. Safety assessment of 6-hydroxyindole as used in cosmetics. Int J Toxicol. 2014;33(3 Suppl):24S-35S. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- 6-Hydroxyindole (Standard)
- 2380-86-1
- Reference Standards
- Biochemical Assay Reagents
- Endogenous Metabolite
- OAT
- Ferroptosis
- glutathione
- HT-22 mouse hippocampal neurons
- OATP1B1
- HEK293/OATP1B1 cells
- organic anion transporting polypeptide 1B1
- blood-brain barrier
- N27 rat dopaminergic neurons
- neurodegenerative diseases
- renal failure
- ferroptosis
- Inhibitor
- inhibitor
- inhibit