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Cat. No.: HY-149216

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Anticancer agent 103

Anticancer agent 103 (Compound 2k) is a potent anticancer agent.

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CAS No.: 2914922-78-2
화학식: C₁₈H₂₀BrN₃O
분자량:374.27

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Anticancer agent 103 Chemical Structure

CAS No.: 2914922-78-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Anticancer agent 103 (Compound 2k) is a potent anticancer agent^[1].

In Vitro

Anticancer agent 103 (Compound 2k; 12.5-400 μM; 24 or 48 h) inhibits HepG2 cell viability, but not Colo-205 viability^[1].
Anticancer agent 103 (25 and 50 μM; 24 h) increases the FoXO1, TXNIP and p27 protein levels in HepG2 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

HepG2 and Colo-205 cells
Concentration:

12.5, 25, 50, 100, 200 and 400 μM
Incubation Time:

24 or 48 h
Result:

Demonstrated anticancer activity against cancer cell line HepG2 with IC₅₀s of 30.5 μM and 14.8 μM for 24h and 48 h, respectively. The IC₅₀ for Colo-205 was >400 μM.

Western Blot Analysis^[1]

Cell Line:

HepG2 cells
Concentration:

25 and 50 μM
Incubation Time:

24 h
Result:

Increased the FoXO1, TXNIP and p27 protein levels.

Chemical Information

CAS No. 2914922-78-2
분자량 374.27
화학식 C₁₈H₂₀BrN₃O
SMILES

O=C(C1=CC=C(NCCCC)C=C1)N/N=C/C2=CC=C(C=C2)Br
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Han Mİ, et al. Design, Synthesis, and Anticancer Evaluation of Novel Tetracaine Hydrazide-Hydrazones. ACS Omega. 2023 Feb 28;8(10):9198-9211. [Content Brief]

Calculators

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Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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