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Cat. No.: HY-112603A

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AP5 sodium

2 Cited Publications

고객리뷰

Based on 2 publication(s) in Google Scholar

AP5 sodium is a potent, orall active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 sodium demonstrates rat and human inositol monophosphate (IP1) EC₅₀ values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 sodium has the potential for type II diabetes research.

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CAS No.: 1623143-67-8
화학식: C₂₈H₂₇FNNaO₄
분자량:483.51

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

AP5 sodium Chemical Structure

CAS No.: 1623143-67-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information

CAS No. 1623143-67-8
분자량 483.51
화학식 C₂₈H₂₇FNNaO₄
SMILES

FC1=CC(C2=CC(OC)=NC=C2)=CC=C1[C@@H]3CCC(C=CC([C@H](C4CC4)[C@H](C)C(O[Na])=O)=C5)=C5O3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Nat Neurosci

Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus. [Abstract]

2023 May;26(5):751-764. PMID: 36973513
Nat Commun

A non-canonical visual cortical-entorhinal pathway contributes to spatial navigation. [Abstract]

2024 May 15;15(1):4122. PMID: 38750027

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chen HY, et al. Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs. ACS Med Chem Lett. 2018 Jun 14;9(7):685-690. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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AP5 sodium

2 Cited Publications

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Publications (2)
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AP5 sodium

Publications Citing Use of MedChemExpress (MCE) AP5 sodium

All Free Fatty Acid Receptor Isoforms

Biological Activity

Chemical Information

Publications (2)

순도&문서

References

Calculators

Help & FAQs

AP5 sodium Related Classifications

HY-112603A Related Classifications