Aspergillusidone D
Aspergillusidone D (Compound 1), a brominated depsidone, is a Aromatase inhibitor with an IC50 of 0.8 μM. Aspergillusidone D can be isolated from fungus Aspergillus unguis cultured in KBr medium. Aspergillusidone D has potent cytotoxicity against cancers cells, such as MOLT-3 cells. Aspergillusidone D can be used for cancers like breast cancer research.
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- CAS No.: 1454585-77-3
- 화학식: C19H16Br2O5
- 분자량:484.14
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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Aromatase 0.8 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
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| RAW264.7 | IC50 |
23.72 μM
Compound: 1
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 15 mins prior to LPS challenge measured after 20 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 15 mins prior to LPS challenge measured after 20 hrs by Griess assay
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[PMID: 24016057] |
Chemical Information
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CAS No. 1454585-77-3
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분자량 484.14
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화학식 C19H16Br2O5
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SMILES
C/C=C(C1=C2C(OC(C3=C(C)C(Br)=C(O)C=C3O2)=O)=C(C(O)=C1Br)C)\C
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Structure Classification
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Initial Source
Aspergillus unguis
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Aspergillusidone D Related Classifications
HY-N16402 Related Classifications
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