BACE2-IN-1
Based on 1 Customer Validation
BACE2-IN-1 (compound 3l) is a highly selective BACE2 inhibitor with a Ki value of 1.6 nM. BACE2 inhibitors can be used to research of Type 2 Diabetes.
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- Purity: 99.4%
- CAS No.: 1676107-08-6
- 화학식: C36H38F3N3O3
- 분자량:617.70
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
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BACE2 1.6 nM (Ki) |
BACE1 815.1 nM (Ki) |
Chemical Information
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CAS No. 1676107-08-6
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Appearance Solid
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분자량 617.70
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화학식 C36H38F3N3O3
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Color White to off-white
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SMILES
O=C(C1=CC(C)=CC(C(N[C@@H](CC2=CC=CC=C2)[C@H](O)CNCC3=CC=CC(C(F)(F)F)=C3)=O)=C1)N(C)[C@@H](C4=CC=CC=C4)C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 62 mg/mL (100.37 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6189 mL | 8.0945 mL | 16.1891 mL | 40.4727 mL |
| 5 mM | 0.3238 mL | 1.6189 mL | 3.2378 mL | 8.0945 mL | |
| 10 mM | 0.1619 mL | 0.8095 mL | 1.6189 mL | 4.0473 mL | |
| 15 mM | 0.1079 mL | 0.5396 mL | 1.0793 mL | 2.6982 mL | |
| 20 mM | 0.0809 mL | 0.4047 mL | 0.8095 mL | 2.0236 mL | |
| 25 mM | 0.0648 mL | 0.3238 mL | 0.6476 mL | 1.6189 mL | |
| 30 mM | 0.0540 mL | 0.2698 mL | 0.5396 mL | 1.3491 mL | |
| 40 mM | 0.0405 mL | 0.2024 mL | 0.4047 mL | 1.0118 mL | |
| 50 mM | 0.0324 mL | 0.1619 mL | 0.3238 mL | 0.8095 mL | |
| 60 mM | 0.0270 mL | 0.1349 mL | 0.2698 mL | 0.6745 mL | |
| 80 mM | 0.0202 mL | 0.1012 mL | 0.2024 mL | 0.5059 mL | |
| 100 mM | 0.0162 mL | 0.0809 mL | 0.1619 mL | 0.4047 mL |
BACE2-IN-1 Related Classifications
HY-136742 Related Classifications
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