Brimarafenib
Based on 1 Customer Validation
Brimarafenib is a rapidly accelerated fibrosarcoma (Raf) kinase inhibitor wtih antineoplastic effect.
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- Purity : 99.35%
- CAS No.: 1643326-82-2
- 화학식: C24H17F3N4O4
- 분자량:482.41
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Chemical Information
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CAS No. 1643326-82-2
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Appearance Solid
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분자량 482.41
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화학식 C24H17F3N4O4
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Color White to off-white
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SMILES
FC(C=C(C(F)=C1)F)=C1NC(N[C@H]2[C@@]3([H])[C@]2([H])OC4=CC=C(OC5=C6C(NC=C5)=NC(CC6)=O)C=C43)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
용액&용해도
In Vitro:
DMSO : 33.33 mg/mL (69.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0729 mL | 10.3646 mL | 20.7293 mL | 51.8231 mL |
| 5 mM | 0.4146 mL | 2.0729 mL | 4.1459 mL | 10.3646 mL | |
| 10 mM | 0.2073 mL | 1.0365 mL | 2.0729 mL | 5.1823 mL | |
| 15 mM | 0.1382 mL | 0.6910 mL | 1.3820 mL | 3.4549 mL | |
| 20 mM | 0.1036 mL | 0.5182 mL | 1.0365 mL | 2.5912 mL | |
| 25 mM | 0.0829 mL | 0.4146 mL | 0.8292 mL | 2.0729 mL | |
| 30 mM | 0.0691 mL | 0.3455 mL | 0.6910 mL | 1.7274 mL | |
| 40 mM | 0.0518 mL | 0.2591 mL | 0.5182 mL | 1.2956 mL | |
| 50 mM | 0.0415 mL | 0.2073 mL | 0.4146 mL | 1.0365 mL | |
| 60 mM | 0.0345 mL | 0.1727 mL | 0.3455 mL | 0.8637 mL |