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C3 sodium

C3 sodium is an aptamer that binds to Erk2. C3 binds to the MAP kinase insert domain, a unique site on Erk1/2. Due to this recognition profile C3 inhibits Erk2 activation by its upstream kinase MKK1.

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  • C3 sodium Chemical Structure
    C3 sodium Chemical Structure
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  • C3 sodium Chemical Structure
    C3 sodium Chemical Structure RNA, 5'-CUGCAGUUCGGGUAGCACACGAAGGGCACCGUAGCAAUACGGUUGUUCUGGUUAAC-3', sodium salt
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  • RNA, 5'-CUGCAGUUCGGGUAGCACACGAAGGGCACCGUAGCAAUACGGUUGUUCUGGUUAAC-3', sodium salt